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  • Volume 7, Issue 4
  • Volume 7, Issue 4

    1407bow News Aydogan Ozcan
    Bioimaging

    MOBILE HEALTH: Strategies in Biophotonics keynoter Ozcan named HHMI professor

    July 30, 2014
    Aydogan Ozcan, Chancellor's Professor of electrical engineering and bioengineering at UCLA (Los Angeles, CA), is one of 15 researchers from around the country to be named a 2014...
    1407end Fig1
    Bioimaging

    Veterinary ophthalmology's new tool: OCT

    July 30, 2014
    Now, prices have reached a threshold where optical coherence tomography (OCT) can be used by care providers not just for humans, but also for companion animals.
    1407end Fig2
    Biophotonics Tools

    Laser device can slay sea lice on farmed salmon noninvasively

    July 30, 2014
    Knowing that sea lice are a threat to salmon farms and surrounding sea life, Stingray Marine Solutions AS (Oslo, Norway) has developed a submersible device that they call Optical...
    Images courtesy of Erickson Lab, Cornell University
    FIGURE 1. A solar thermal PCR system converts sunlight into heat to drive DNA amplification (a) within a microfluidic channel (b, c). A smartphone app reads the on-chip temperatures (d) and performs fluorescence detection of the amplified sample (e).
    Bioimaging

    OPTOFLUIDICS: Optofluidics and the next generation of health-care engineering

    July 29, 2014
    Instruments that can do medical diagnoses at home or other places far from hospitals are the wave of the future. Optofluidic devices, some of which can be used with smartphones...
    FIGURE 1. PA signal generation and detection.
    Fluorescence

    VIBRATIONAL PHOTOACOUSTIC MICROSCOPY: Converting molecular vibration to mechanical for deep-tissue imaging

    July 29, 2014
    An emerging label-free imaging modality with chemical selectivity and millimeter-deep resolvability, vibrational photoacoustics (VPA) provides a new avenue to map chemical content...

    More content from Volume 7, Issue 4

    FIGURE 1. A typical neuron, with extensions to the cell body, is shown in its presynaptic state. The region where an axon terminal/ending communicates with its postsynaptic target cell is known as a synapse.
    Fluorescence

    HIGH-SPEED IMAGING: Choosing components to image intracellular signals

    July 29, 2014
    High-performance sensors, lenses, and light modules are enabling an unprecedented ability to image action potentials. Building a system to capture these important event triggers...
    (Adapted from Reference 6)
    FIGURE 1. The ms-TRFS experimental configuration includes optical pass-band filters with center wavelength/bandwidth: 390/40, 452/45, 542/50, 629/53 nm, respectively (F1 to F4). BS1 to BS4 are dichroic beamsplitters with greater than 93% transmittance for wavelengths longer than 360, 420, 510, and 590 nm, respectively. The system also includes a wavelength selection module, multimode fiber-optic delay lines, and fluorescence detection components. All elements of the fiber selection module are mounted on a compact, 36 × 165 mm breadboard. A FLIm image results from an x-y scan.
    Fluorescence

    FLUORESCENCE SPECTROSCOPY/BIOMEDICAL IMAGING: Fluorescence 'lifetime' moves toward clinical application

    July 29, 2014
    Time-resolved ("lifetime") fluorescence spectroscopy and imaging provide label-free optical molecular contrast of diseased tissues and outperform steady-state fluorescence. Now...
    (Image courtesy of Leica Microsystems)
    FIGURE 1. DMshare, which 'has revolutionized how things go in my classroom,' according to Maria Moreno of Yale, distributes microscope images to iPads.
    Bioimaging

    MICROSCOPY: Advancing microscopy with apps

    July 29, 2014
    Enabling control of imaging devices and easy image sharing, apps for smartphones and tablets are revolutionizing education involving microscopy. In the future, they will likely...
    Adapted from Reference 9
    FIGURE 1. Views of the fiber-based high-density DOT system cap from (a) the side and (b) above. The FOV of system on the brain can vary, given a subject's head size and shape. The panel in (c) shows where on the brain the system is sensitive on eight representative subjects.
    Bioimaging

    HIGH-DENSITY DIFFUSE OPTICAL TOMOGRAPHY: Imaging distributed function and networks in the human brain

    July 29, 2014
    Functional neuroimaging via optical methods offers many advantages—safety, implant compatibility, affordability, and potential portability—over traditional PET- and MRI-based ...
    1407bow News Mdea Ninepoint
    Bioimaging

    LIGHT-ENABLED DENTISTRY/OPTICAL COHERENCE TOMOGRAPHY: Biophotonics systems honored with Medical Design Excellence Awards

    July 29, 2014
    Convergent Dental Inc.'s (Natick, MA) Solea laser system—which, at 9.3 μm, is the first CO2 laser system ever cleared by the FDA for hard and soft tissue ablation—took a Gold ...
    A tour of Erasmus University Medical Center departments reminded members of the European Photonics Industry Consortium (EPIC) that when designing medical photonic devices, it is important to gain direct insight in the working circumstances of medical professionals.
    Bioimaging

    ONCOLOGY/SURGICAL GUIDANCE: Photonics answers important questions in surgical guidance

    July 29, 2014
    Can we reduce cancer recurrences with tools to enable more precise surgical resection? That was the major question of a workshop, organized by the European Photonics Industry ...
    1407bowbreak Fig6
    Biomedicine

    PLASMONICS/DIABETES MANAGEMENT: Biosensor aims to measure glucose in saliva

    July 29, 2014
    A new chip-based biosensor hopes to one day allow people with diabetes to measure their glucose using saliva-and do away with needle sticks. And it promises other applications...
    1407bowbreak Fig5
    Biomedicine

    VITAL SIGNS MONITORING: Speckle effect enables noninvasive glucose, pulse readings

    July 29, 2014
    In papers published by Biomedical Optics Express, groups of researchers from the Netherlands and Israel describe two new wearable devices that use changing patterns of scattered...
    1407bowbreakf4
    Bioimaging

    DEEP-TISSUE IMAGING: Signal processing-enhanced, single-pixel optical system images deeper

    July 29, 2014
    If only light were able to penetrate all the way through the body's tissues, the many advantages of optical imaging could become even more valuable.
    1407bowbreakf2
    Biomedicine

    DENTISTRY/REGENERATIVE MEDICINE: Low-level light stirs in vivo stem cells to regenerate tissue

    July 29, 2014
    Researchers have demonstrated for the first time that noninvasive, low-power light therapy can prompt stem cells inside the body to reconstruct tissue.
    1407bowbreak Fig1
    Neuroscience

    OPTOGENETICS: Noninvasive optogenetics potentially promising for human applications

    July 29, 2014
    Optogenetics, which lets scientists control brain activity by shining light on neurons, involves light-sensitive proteins (to suppress or stimulate signals within cells) and-traditional...
    1407bowbreak Fig3
    Biomedicine

    PHOTODYNAMIC THERAPY/CANCER TREATMENT: SHG takes PDT to deep-lying tumors

    July 29, 2014
    Noninvasive photodynamic therapy (PDT) is very precise and boasts no long-term side effects. But because it typically uses visible light, it is normally effective only for the...
    Barbaragoode2
    Bioimaging

    Speaking of mHealth

    July 29, 2014
    In a new market report on the mobile health (mHealth) market, Lux Research (Boston, MA) says that once mobile clinical devices clear regulatory hurdles and physicians embrace ...